Genomics
Genome Assembly and Annotation
De novo genome assembly and annotation of small and medium-sized genomes.
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Variant Calling and Annotation
Detection of genetic markers in a cohort of individuals from DNA sequence data.
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Natural Selection Analysis
Understanding how DNA sequences have changed due to natural selection.
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Phylogenetic Analysis
Construction of a phylogenetic tree from DNA sequences of multiple species.
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Microbiome Analysis
Understanding the role of microbial communities in diseases and overall health.
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Epigenetics
DNA–Methylation Analysis
Identifying and understanding the function of methylated regions at single-base resolution across the entire genome using BS-seq or MeDIP-seq data.
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DNA–Protein Binding Sequence Analysis
Identifying and understanding the function of transcription factors and histone modifications across the entire genome using ChIP-seq data.
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Chromatin Accessibility Analysis
Identifying regions of open chromatin across the entire genome and understanding how chromatin packaging affects gene expressions using ATAC-seq data.
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Chromatin Interaction Analysis
Identifying chromatin conformation structures from a genome-wide 3D capture and understanding how chromatin interactions are associated with the regulation of gene expressions using Hi-C data.
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Transcriptomics
RNA Sequence Analysis
Understanding how gene expression profiles vary between health and disease conditions using RNA-seq or scRNA-seq data.
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RNA Structure Prediction
Prediction of a two-dimensional RNA secondary structure from an RNA base sequence.
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Proteomics
Mass Spectrometry-Based Proteomic Analysis
Understanding and quantitation of mass spectrometry-based proteomic data.
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Protein Function Prediction
Prediction of protein functions from protein sequence data.
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Metabolomics
Mass Spectrometry-Based Metabolomic Analysis
Understanding and interpretation of mass spectrometry-based metabolite data.
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Translational Bioinformatics
Genome Wide Association Analysis
Identification of genetic variants associated with a phenotype.
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Genome Wide Interaction Analysis
Identification of interacting pairs of genetic variants and their association with a phenotype.
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Multi-Omic Integrative Analysis
Exploration and identification of multiple omic measurements associated with a phenotype.
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Genome Editing
Modifying genomic sequences in eukaryotic cells with new genetic information to study and repair disease-causing DNA mutations.
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