Genome Wide Interaction Analysis
Genome Wide Interaction Analysis (GWIA) involves testing pairs of interacting single nucleotide variants (SNVs) for their association with a binary/quantitative trait or a disease in a case–control study. GWIA is a valuable method for finding the remaining missing heritability undetected by Genome Wide Association Analysis (GWAA).
Requirements
- Genotypic and phenotypic data files
Deliverables
- List of SNV pairs and their corresponding degrees of association with the phenotype.
- Functional enrichment of genes overlapping significantly associated SNV pairs.
Tawftics 